The Best Argireline Cream – 2017 Reviews & Top Picks

In order to help you achieve a younger and healthy skin, we’ve compiled 5 of the best argireline cream products. These creams made our list thanks to their ability to reduce visible signs of skin aging. We believe these products will be secret weapons in your beauty arsenal.

There are so many things in this world that are beyond our control, and one of them is aging.

Yes, we become wiser as we age, but aging can do a number on our skin.

During our late 30’s to early 40’s, unwanted deep creases begin to form on our foreheads, necks and eyes, and wrinkles continue to show up as we age.

As a way to combat the inevitable effects of aging, various serums and formulas have sprung with the promise of youthful, line-free skin.

But the most popular anti-aging cosmetic surgery, called “botox”, proves to be the most efficient of all. However, not all people are willing to go under the needle and spend a hefty price for this procedure.

We say you don’t need a botox treatment when you can opt for the best argireline cream.

Argireline is described by many as “botox in a jar” and for a good reason too – it imparts the same effect as Botox minus the risks of surgery.​

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Quick Overview: Our Top Picks for The Best Argireline Creams

OUR TOP #1 PICK - The best anti-aging cream should not only reduce wrinkles and fine lines, but it should also nourish, heal, and keep the skin healthy like the Andre Lorent Face Cream. It’s our number one pick for the best argireline cream because it combines argireline and Matrixyl – two powerhouse anti-aging compounds.

OUR TOP #2 PICK - The argireline, Retinol, and vitamin C contents of the Rococo Revitalize Anti-aging Cream have the potency to brighten and nourish the skin, subsequently restoring a youthful glow.

OUR TOP #3 PICK - Sagging neck and decollete skin is a big no-no. One of the few firming creams that solve this problem is the YEOUTH Neck Cream. Powered by green tea and vitamin C, this potent cream fights the signs of aging while healing the skin.

OUR TOP #4 PICK - The “turkey neck” syndrome is a common aging skin problem that can be reduced by the SkinPro Neck Firming Cream. Containing squalene and marine collagen, this cream firms the skin while hydrating it at the same time.

OUR TOP #5 PICK - There’s another lesser known anti-aging ingredient in town – it’s DMAE (Dimethylaminoethanol). DMAE, along with MSM and Niacinamide, help argireline lift the skin and achieve a radiant glow. These ingredients are all in our fifth pick, the DNA Code Oil-Free Magic Firming Cream.

What is Argireline and How Does It Work?

Argireline, or Acetyl hexapeptide-3, is a synthetic cosmetic ingredient designed to be applied topically to the face, giving a botox-like effect without having to undergo injections.

Botox treatments have become one of the most enduring trends in defying aging nowadays - it makes the skin more elastic and youthful.

Botox is a drug used for cosmetic surgery to drastically reduce the appearance of wrinkles and fine lines by paralyzing the facial muscles, temporarily.

Some celebrities undergo botox procedures like they’re simply facial massages, making it look as if the process didn’t hurt at all.

Since you’ll be going under the needle for botox, there's a chance that it will burn or sting a bit.

Surgical procedures inevitably come with a few risks and are surely priced heavily. For those who are scared to undergo botox surgeries, argireline is the best alternative.

Argireline and botox have similar peptide compounds. Thus, they work in a similar manner.

The only difference is that botox injections reach even deeper skin layers, whereas argireline creams only penetrate the surface and subsurface skin layer.

In serums and creams, argireline is often the main anti-aging formula mixed with other ingredients that are absorbed into the skin.

After it is absorbed by the skin, argireline lessens the contraction of facial muscles, and this allows you to smile freely without making wrinkles look more prominent.

When used consistently, argireline-based cosmetic products can reduce almost 30% of the fine lines and wrinkles on the face.

Moreover, argireline makes the skin appear younger, and it also makes the skin healthy and hydrated, adding to that youthful glow.

However, individuals with thick skins may find that the cream takes longer to take effect because argireline doesn't go beyond the surface of the skin.

What Makes a Good Argireline cream?​

Argireline creams and serums are widely available in skincare stores and online shops.

Choosing the right argireline cream is fairly simple. Take note of the following criteria when scouting for the best argireline cream:​

  • Argireline should be the primary ingredient in the product. It should be present at around 10-20%. If possible, look for products with more than 20% argireline content. The higher the concentration, the more effective it is.
  • The product should also be quickly absorbed into the skin. Try swatching the product tester on your wrist or lower palm and see if it gets absorbed in a short time without the greasy and heavy feel.
  • If the product leaves an oily film after application, skip it. It will most likely clog the pores and cause unwanted breakouts. Also, argireline creams are best worn both day and night, and nobody wants to walk around with a shiny or shimmering face.
  • Convenient packaging. Convenient packaging makes a big difference. The cream or serum should come in a compact, spill-free, and leak-free container and ideally, it should have a pump for clean and easy dispersal.
  • Most importantly, the product should be highly effective. Your wrinkles and fine lines may be improved by the cream or serum.

The effect may not be as quick as you expect, especially if you have a thick skin, but they should be visible. Also, the product should not have any harmful side effects on the skin.

Product Reviews: Our Top 5 Best Argireline Creams​


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Our Rating


The best anti-aging creams do not only reduce wrinkles and fine lines, but they should also nourish, heal, and keep the skin healthy.

The Andre Lorent Face Cream contains five powerful anti-aging ingredients – argireline, matrixyl, hyaluronic acid, vitamin C, and E.

We chose this product as a candidate for the best argireline cream because it has a high concentration of argireline along with other potent age-defying constituents.

Argireline, or the “natural botox”, rejuvenates the skin and may reduce wrinkles and fine lines, resulting in firmer skin.

Over time, your skin may feel naturally tighter and smoother like what we experienced upon religious application of this cream for almost two weeks.

Another excellent ingredient of this cream is hyaluronic acid. With this acid, the skin can hold exceptionally high amounts of moisture, therefore hydrating the skin for long hours.

For skin healing and improvement, vitamins C and E work simultaneously to treat the skin gently. Vitamin C lightens the skin, fading away dark spots and acne marks.

Adding up to its benefits is the moisturizing and softening effects of vitamin E.

Vitamin E penetrates into the vital skin membranes where it accumulates to enrich skin lipids and reduce the typical inflammation brought on by UV exposure.

What We Like

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    May help reduce wrinkles and fine lines
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    May brighten skin
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    Helps firm and tighten the skin

What We Don't Like

  • Has a thick consistency
  • Product comes in a jar and may be prone to contamination

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Our Rating


The Rococo Revitalize Anti-aging Cream is an all-in-one cream that defies the visible signs of aging, brightens and nourishes the skin.

The collagen protein provides strength and structure to the skin, hair, and muscles by restoring their natural elasticity.

Vitamin C helps to fade away dark spots, balance the skin tone, and treat hyperpigmentation of the skin.

Argireline and retinol are the two primary anti-aging ingredients of this terrific cream. Argireline lessens creases along the forehead and eyes by briefly paralyzing facial muscles, whereas retinol works to tighten the skin through the synthesis of collagen.

Lastly, the hyaluronic acid ingredient deeply moisturizes the skin without leaving an irritating oily film on the face. That’s why we’re in love with this cream – it’s quickly absorbed, and it dries clear.

Our very sensitive skin didn’t break out or reacted negatively to this cream, and we suspect that it may be due to the lack of parabens and sulfates in this product.


What We Like

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    Doesn’t leave a greasy film
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    May work for people with sensitive skin

What We Don't Like

  • It is scented (denotes the presence of chemicals)
  • May cause slight peeling due to the presence of retinol

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Our Rating


If you're having problems with sagging skin on your neck, this third entry on our list of the best argireline creams contains green tea and vitamin C and may help address that.

It’s our one of our favorites because there are only a few products that cater to sagging skin on the neck and upper chest.

Argireline reduces the sagginess of the neck as well as the décolleté skin by lessening the contraction of the muscles in that area.

These areas have thin skin. Thus they’re very prone to damage caused by the aging process.

The good thing about argireline is that the compound quickly seeps into the thin skin layer, hastening the rejuvenation process.

Another abundant ingredient of this cream is green tea, particularly the catechin ECCG. This part is especially helpful with hydrating and healing the cells.

In fact, green tea has been proven to fight premature signs of aging and sun spots caused by long exposures to harmful UV rays.

To further boost the effects of argireline and green tea, vitamin C has been added to the formula.

It’s an antioxidant that has a broad range of benefits including collagen production, moisture retention, skin lightening, and restoration of skin elasticity.

We’ve tested this cream for a time and have not had any adverse reactions to it. However, it may take a while before we see any discernible improvement.

What We Like

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    May work to reduce neck and décolleté skin creases
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    Moisturizes the skin

What We Don't Like

  • May take some time before it gives visible results

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Our Rating


The SkinPro Neck Firming Cream boasts an optimal formula for defying the dreaded “turkey neck” – argireline, retinol, squalene, and marine collagen.

Retinol (vitamin A) teams up with argireline to tighten the neck and chin skin.

Meanwhile, collagen is popular for its ability to reduce the appearance of cellulite and stretch marks and most especially, wrinkles and fine lines.

Furthermore, squalene, which is an oil derived from plant sources, makes the cream easily absorbed by the skin because it’s a natural oil, which keeps the skin soft and supple.

With soft and hydrated skin, the appearance of aging signs will be visibly reduced.

We discovered that the cream doesn’t leave a greasy film after application, which makes it very convenient to wear as a day moisturizer.

This cream also caught our attention primarily because it has marine collagen in it. Marine, or fish, collagen peptides are extracted from fish sources.

Similar to other collagens, fish collagen stimulates collagen synthesis, heals wounds, and regenerates the cells.

Simply put, collagen makes the skin resilient to stressful elements while simultaneously giving it the gentle treatment it deserves.

What We Like

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    May work to firm and tighten the neck skin
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    Fragrance and chemical-free

What We Don't Like

  • May take some time before it gives visible results
  • May cause slight itching and redness

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Our Rating


By now, you’re familiar with almost every age-defying powerhouse ingredient – argireline, vitamin C, and collagen for example.

But this particular cream sets itself apart from other argireline creams as it has DMAE, MSM, Niacinamide (Vitamin B3), and hyaluronic acid in its formulation.

The triple combo helps argireline to lift the skin. That’s why this product made it to our best argireline creams list. The combo works cumulatively to make the skin appear radiant, healthy, and glowing.

DMAE has been rising in popularity as an effective skin lifting ingredient due to advertisements by skin care giants. But does it truly work?

Our curiosity led us to test this cream for over a week, and it worked to tighten our facial skin a little. Consistent application of the product over a few weeks may yield visible results.

Aside from DMAE, MSM and Niacinamide also play a role in skin lifting. MSM has been proven to detoxify, strengthen and improve skin elasticity through the production of collagen and keratin to restore dry, cracked, and aging skin.

Niacinamide boosts the skin’s immunity, improves skin blotchiness, helps even out the skin tone, and reduces wrinkles and lines.

The niacinamide antioxidant also helps fight off free radicals, reversing the onslaught of dull skin.

Lastly, this product contains hyaluronic acid. While the other ingredients work to firm and tighten the skin, hyaluronic acid provides moisture to the skin, thereby nourishing it in the process.

What We Like

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    Contains more age-defying ingredients other than argireline and collagen
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    Oil-free

What We Don't Like

  • Has a thick consistency
  • May take some time before it gives visible results

The Bottom Line

Our top choice for the best argireline cream is none other than Andre Lorent Face Cream.

This fantastic cream can also double as a day or night moisturizer because it’s laced with hyaluronic acid.

It visibly reduces wrinkles and fine lines with its two powerful anti-aging ingredients, argireline and matrixyl.

Aside from restoring the elasticity of the skin, this cream also helps fade away dark spots and reduce hyperpigmentation, thanks to its vitamin C content.

While concurrently tightening and lightening the skin, vitamin E supplies the much-needed moisture and nourishment of aging and dull skin, the final step to achieving that youthful glow.​